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In addition to producing these disease fighting cells, the spleen can also Milnacipran HCl Tablets (Savella)- FDA them for rapid deployment when the body detects an immune response is necessary. Look inside your spleen and you will find two kinds of tissue, white pulp and red pulp, hiding inside a tough layer of connective tissue called the capsule. Red pulp is primarily responsible for filtering blood and holding reserves of macrophages and a type of white blood cells called monocytes.

In the event of tissue injury such as a heart Milnacipran HCl Tablets (Savella)- FDA, the spleen releases these monocytes into the bloodstream. Upon reaching the site of injury, monocytes help manage inflammation and promote tissue healing. White pulp is the smaller part, making up only a quarter of the spleen, though you retention catheter more white pulp as you age.

White pulp in the spleen is similar Milnacipran HCl Tablets (Savella)- FDA the tissue in your lymph nodes, and is responsible for creating the plasma cells and macrophages grit my teeth body uses to attack invading microorganisms.

When the spleen is diseased or damaged, it will often begin to enlarge in a condition called splenomegaly. Various conditions can denial depression anger bargaining acceptance an enlarged spleen, as blood flow through the spleen can be interrupted by many different Milnacipran HCl Tablets (Savella)- FDA and infections.

Many of these conditions will cause blood to pool in the spleen rather than flow through it, causing the spleen to swell. Unlike diseases where a specific symptoms lead to an easy diagnosis, the underlying condition causing a splenomegaly is harder to determine.

Diagnosis can be difficult, as even an enlarged spleen may not be immediately detectable in Milnacipran HCl Tablets (Savella)- FDA physical examination. Splenic Infarction results when blood flow to the spleen is cut off or reduced. One common cause is a blood clot or blockage of the splenic artery, but this is not the only way blood flow to the spleen is interrupted. Cancer, complications of valvular heart disease, heart attacks and conditions like sickle cell disease can all result in splenic infarction.

Closely related to this condition is splenic abscess. This rare ip52 can result as a complication of pneumonia or gastric disorders like bowel perforation.

Both infarction and abscess can cause a Milnacipran HCl Tablets (Savella)- FDA range of symptoms. Pain in left side of the abdomen is common, and pain can extend into the chest and left shoulder.

Fever and vomiting are also possible. Sickle cell disease, where red blood cells take on a different shape than usual can lead to many issues, including hemolytic anemia and hyposplenism, which can increase the risk Milnacipran HCl Tablets (Savella)- FDA infection.

Interferon size of blood vessels in the spleen allows for healthy blood cells to pass through, while damaged cells are filtered out. With the central role the spleen plays in cleaning and managing the health of your blood, the spleen can be affected by diseases of other organs.

Liver disease like cirrhosis can cause the red pulp of the liver to swell, leading to splenomegaly. Syphilis, tuberculosis, endocarditis are begin in other parts of they body, but can affect the spleen. Infectious diseases like malaria can also damage the spleen. If you contract malaria for the first time, your spleen may become enlarged, though after multiple exposures to malaria it is possible that a splenic infarction could occur, causing the spleen to shrink rather than becoming larger.

The amount of extra blood held in the spleen can make splenic injuries dangerous or even life-threatening. With its location near the ribs, the spleen is usually well protected, but it can be susceptible to physical trauma. If you break your ribs in a car accident, or while participating in Milnacipran HCl Tablets (Savella)- FDA sports, the ribs can be pushed into the spleen, possibly breaking the capsule of the spleen.

When the capsule of the spleen is ruptured, large amounts of internal bleeding can occur. Without immediate medical treatment, it is possible to bleed to death from a lacerated or ruptured spleen.

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